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What Sleep Medication Should I Take?

Published: Jan 28, 2025
Updated: Jan 28, 2025
What Sleep Medication Should I Take?
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    Many various factors can contribute to someone not being able to sleep well at night. Besides making changes to your lifestyle and sleeping habits, some may turn to sleeping pills and medication as a temporary solution. But, the question is— how do you know which is the right sleep medication for you to take?

    In this article, we’ll explore the different types of sleep medications available, the benefits and risks along with some alternative solutions if you’re looking to avoid the use of sleep aids.

    Key Takeaways
    Sleep medications or sleeping pills are used to help those with insomnia or trouble falling asleep to be able to get a good night’s rest.
    Sleeping pills can be divided into two categories which are prescription sleeping pills and non-prescription sleeping pills, also known as over-the-counter (OTC) sleeping pills.
    Benzodiazepines are one of the most commonly prescribed medications that produce a sedation effect and reduce anxiety for improved sleep.
    Common side effects of taking sleep medicines include dizziness, nausea, diarrhea, drowsiness, allergic reactions, muscle weakness,s and cognitive issues.
    Consider cognitive behavioral therapy for insomnia (CBT-I) or practice good sleep habits as alternative solutions to medications.

    What is Sleep Medication?

    what is sleep medication

    Sleep medication, in broad terms, is a type of medication that helps individuals to fall asleep and stay asleep at night. It is often recognized to be synonymous with sleeping pills.

    Classifying Sleeping Pills

    Sleeping pills are medications used to help people with sleep disorders such as insomnia or those with trouble sleeping to be able to sleep soundly at night.

    They can be classified into two main categories— prescription sleeping pills and non-prescription sleeping pills. From here, it is further broken down into different sub-categories based on their chemical structure and mechanism of action [1].

    Types of Prescription Sleeping Pills

    benzodiazepines is a type of prescription sleeping pill

    Under prescription sleeping pills, there are many different types of medications that can be classified as sedative-hypnotics. These are medicines that work by increasing the activity of GABA, a neurotransmitter that sends signals to the brain [2].

    Benzodiazepines are the most common type of sedative-hypnotics that produce sedation, muscle relaxation and reduce anxiety which helps you fall asleep faster. They are generally recommended as a short-term treatment option for insomnia. Some approved benzodiazepines include estazolam, flurazepam, temazepam, triazolam [3], [4].

    Other common prescription sleeping pills include zopiclone and zolpidem, where the effect may be similar to benzodiazepines.

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    Types of Non-Prescription Sleeping Pills

    yellow bottle with a label that says melatonin and several yellow pills scattered beside it

    There are also non-prescription sleeping pills or over-the-counter (OTC) sleep aids that are widely available to those looking for short-term relief but without having to deal with serious side effects. Standard non-prescription medicines rely on antihistamines as a primary ingredient to promote drowsiness.

    Common sleeping aids that you’ll find over the counter include [3]:

    • Diphenhydramine
    • Doxylamine
    • Melatonin
    • Valerian

    Benefits and Risks

    The main benefits of taking these sleep medicines are that they can either help you fall asleep stay asleep, or both. However, it’s also important to note that most of them can lead to dependency when used in the long run.

    In addition, depending on the type of medication that you are using, there may be some side effects including [5]:

    • Dizziness or headache
    • Nausea
    • Diarrhea
    • Prolonged drowsiness
    • Allergic reaction (e.g. dry mouth)
    • Issues in daytime memory or performance
    • Muscle weakness

    Safety Considerations

    When considering taking sleep aids, it’s important to prioritize your safety to avoid any risks or complications. Some key factors you want to keep in mind would be:

    1. Consulting with a doctor: Before starting any new medications, it’s important to speak to your doctor so that they can recommend the best option for you.
    2. Following prescription labels: Take any medications exactly as prescribed on the label. You want to avoid experiencing adverse effects or over-dependency.
    3. Avoid combining with other medicines: Do not combine it with alcohol or any other medications that you are taking as it may heighten side effects and put you at risk of adverse effects.
    4. Avoid prolonged use: Sleep aids are typically intended to be used only for the short term. Prolonged use can lead to dependency or rebound insomnia if you stop taking them abruptly.

    Older adults and pregnant individuals should be especially cautious when it comes to taking any sleep supplements as there are increased risk and higher sensitivities.

    What is the safest long-term sleep medication?
    Newer hypnotics like zolpidem and zaleplon may be used on a long-term basis with minimal side effects to induce sleep. They are benzodiazepines-like agents with fewer side effects in comparison.
    Dr. Dan Rifkin
    MD, MPH, FAASM Sleep Medicine Expert Physician & Neurologist
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    Alternative Solutions to Sleeping Pills or Sleep Medicine

    woman with eye mask around her forehead and sleeping on the bed, forming good sleep habits which is an alternative to sleeping pills

    For those who don’t wish to use sleeping pills or any form of medication due to the potential side effects, you may consider the use of solutions such as cognitive behavioral therapy for insomnia (CBT-I) or cultivating good sleep habits.

    Cognitive behavioral therapy for insomnia (CBT-I) is a treatment method that targets sleep difficulties and behaviors that contribute to this sleep disorder over a few sessions [6]. It is also commonly used as a first-line treatment for chronic insomnia in adults [7].

    Alternatively, you can also practice good sleep habits such as following a consistent sleep schedule, limiting daytime naps, managing stress or creating a relaxing bedtime routine, to name a few. Good sleep habits can contribute to lowered stress levels and result in improved sleep quality.

    Conclusion

    In short, sleeping pills can be useful in managing insomnia symptoms such as trouble falling asleep. However, it is important to note that they are only temporary solutions. Identifying the underlying cause and creating good sleep habits can help to promote better sleep in the long term.

    Explore and learn sleep methods and tools to improve your sleep experience with the ShutEye® app. ShutEye® is a patented sleep-tracking app that tracks your sleep and creates a personalized sleep plan for you to achieve healthy rest. Try it FREE!

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    FAQ

    The best pill for sleep is dependent on your current condition and sleep history. Typically, a doctor will assess your sleep quality and form a recommendation.

    Benzodiazepines are considered to be the best and most suitable medicine for anxiety and sleep as it signals the brain to reduce anxiety.

    Benzodiazepines and non-benzodiazepines hypnotics are probably the most commonly prescribed medication for sleep.
    About authors
    Amirah is a content writer passionate about topics related to mental health and wellness. Recently, she delved into the realm of sleep health, spurred by a personal recognition of her subpar sleep habits and a desire for improvement. Amirah holds a Bachelor’s Degree in International Communication Studies from the University of Nottingham.
    Dr. Dan Rifkin, MD, MPH, is the founder and CEO of Ognomy, the first healthcare service to entirely shift the diagnosis and care of sleep apnea from a clinical setting to the home. He is a board-certified neurologist and sleep specialist with more than 25 years of experience in sleep medicine.

    Akkayagorn, L. (2023) Sleeping pills - Side effect & Treatments [online]. Available at: https://www.medparkhospital.com/en-US/lifestyles/sleeping-pills

    American Academy of Sleep Medicine (2024) Digital cognitive behavioral therapy for insomnia: Platforms and characteristics [online]. Available at: https://aasm.org/digital-cognitive-behavioral-therapy-for-insomnia-platforms-and-characteristics/

    Better Health Channel (2023) Benzodiazepines [online]. Available at: https://www.betterhealth.vic.gov.au/health/healthyliving/benzodiazepines

    Khan, S. (n.d.) How Do Sedative/Hypnotics Work? [online]. Available at: https://www.rxlist.com/sedativehypnotics/drug-class.htm

    Mayo Clinic (2022) Prescription sleeping pills: What's right for you? [online]. Available at: https://www.mayoclinic.org/diseases-conditions/insomnia/in-depth/sleeping-pills/art-20043959

    Smith, M. and Robinson, L. (2025) Sleeping Pills and Natural Sleep Aids [online]. Available at: https://www.helpguide.org/wellness/sleep/sleeping-pills-and-natural-sleep-aids

    Walker, J., Muench, A., Perlis, M. L., & Vargas, I. (2022) Cognitive Behavioral Therapy for Insomnia (CBT-I): A Primer. Klinicheskaia i Spetsial'naia Psikhologiia = Clinical Psychology and Special Education11(2)123. Available at: https://doi.org/10.17759/cpse.2022110208

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