

As a female, have you ever felt tired all of a sudden? One moment you feel fine, but the next moment, the tiredness comes crashing down on you. What causes sudden crashing fatigue to occur, especially for females?
This article will address this puzzling question by exploring the common causes, implications, and different ways to manage it.
Sudden crashing fatigue can be described as a sudden feeling of extreme tiredness. It may feel like a brain fog, disrupting your ability to perform daily activities.
Females tend to experience this compared to males as they are more susceptible to changing hormone levels, stress, and other underlying health issues.
Fatigue is commonly experienced when a woman goes through menstruation, peri-menopause, and menopause due to hormonal imbalances.
Menstruation is a natural part of life that a woman will experience throughout her reproductive years. The menstrual cycle can be classified into two phases, the follicular phase and the luteal phase. During the menstrual cycle, estrogen levels rise during the mid-follicular phase and fall after ovulation. It will then rise again during the mid-luteal phase and fall towards the end of the menstrual cycle [1], [2].
As the hormones continuously fluctuate, she is bound to also witness fluctuating emotions and energy levels.
In the later parts of her years, the transitional period leading up to menopause is known as perimenopause. During this time, a woman may go through various changes and symptoms such as increased tiredness, insomnia, hot flashes, and anxiety. Estrogen and progesterone will stop being produced, throwing off the rest of the hormones within the body. This transition also causes menopause fatigue [3].
There are two types of thyroid disorders, which are hyperthyroidism and hypothyroidism. Hypothyroidism is when your thyroid glands are not producing enough hormones. Conversely, hyperthyroidism is when your thyroid glands are overproducing hormones.
The thyroid hormones play an important role in ensuring that metabolism, temperature regulation, and proper GI functioning take place. To overcome this, you may be required to take anti-thyroid medications or have surgery, depending on your condition and severity [4].
Iron deficiency anaemia is a type of condition in which there is a lack of iron in your body. Our body needs iron so that it can produce red blood cells which are necessary for helping to store and carry oxygen in the blood.
When you don’t have enough oxygen, it can lead to a lower amount of oxygen being transported in your blood. Common symptoms of iron deficiency anaemia include lethargy, dizziness, and paleness.
This condition can affect women if they are experiencing heavy menstrual periods or if they are bleeding during childbirth [5].
Autoimmune diseases affect as many as up to 20 million individuals in the United States, and there seems to be a strong correlation between sleep and autoimmune diseases, predominantly in women. Conditions like lupus, rheumatoid arthritis, and Hashimoto’s thyroiditis are more prevalent in females and often come with extreme fatigue [6].
Unlike general tiredness, those with autoimmune diseases may experience frequent sleep disturbances. There’s also a higher susceptibility to sleep apnea and REM sleep behavior disorder for those with rheumatoid arthritis, lupus, and multiple sclerosis.
Some of the common symptoms of sudden crashing fatigue in females may include:
These symptoms may also be accompanied by other symptoms such as anxiety, insomnia, weight gain, or brain fog.
Sudden crashing fatigue isn’t just about feeling tired — it can have a ripple effect on your physical, emotional, and mental well-being. For many women, especially those navigating hormonal shifts or underlying health conditions, these episodes can feel unpredictable and debilitating.
Some of the implications of sudden crashing fatigue are:
Chronic Fatigue Syndrome (CFS) is a chronic condition that can interfere with your normal life activities. The real cause of it is not yet understood, but it is commonly suggested that infections can be a trigger.
Chronic Fatigue Syndrome (CFS) is commonly associated with symptoms of sudden and extreme fatigue.
For women who are experiencing menopausal fatigue or fatigue related to hormonal fluctuations, hormone replacement therapy (HRT) can be considered for relieving symptoms.
If you have any underlying medical conditions that are contributing to your fatigue, such as diabetes or sleep apnea, you may want to consider getting the proper medical treatments to address them first and monitor to see if your fatigue improves.
When it comes to dealing with fatigue symptoms, there are a few natural solutions to help you manage them, such as making lifestyle changes and practicing good sleep hygiene.
Here are 4 natural solutions for your consideration:
For women who have worsening symptoms of sudden crashing fatigue or fatigue that continues to persist, consider seeking advice from a doctor who can help to determine if it is a result of underlying medical conditions and provide you with possible treatment options.
To sum up, there are many possible reasons why females may experience extreme fatigue all of a sudden. It could be a menopause symptom, a problem with your thyroid glands, or an underlying medical condition. However, it is also easily managed with the right treatment and good sleep hygiene.
Alternatively, you may consider trying out the ShutEye® app. ShutEye® is an advanced sleep-tracking app that analyzes your sleep patterns and offers personalized solutions to help you improve it naturally. Try it now for FREE!
Amin, S. (2021) Causes and treatment for menopause fatigue [online]. Available at: https://www.medicalnewstoday.com/articles/menopause-fatigue
Brantelid IE, Nilvér H, Alehagen S (2014) Menstruation during a lifespan: A qualitative study of women's experiences. Health Care Women Int, 35(6):600-16 [online]. Available at: https://pubmed.ncbi.nlm.nih.gov/24313552/
National Heart, Lung and Blood Institute (2022) Iron-Deficiency Anemia [online]. Available at: https://www.nhlbi.nih.gov/health/anemia/iron-deficiency-anemia
Reed, B. G. and Carr, B. R. (2018) The Normal Menstrual Cycle and the Control of Ovulation [online]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK279054/
SingHealth (n.d.) Thyroid Disorders [online]. Available at: https://www.singhealth.com.sg/patient-care/conditions-treatments/thyroid-disorders
Zielinski, M. R., Systrom, D. M., and Rose, N. R. (2019) Fatigue, Sleep, and Autoimmune and Related Disorders. Frontiers in Immunology, 10, 1827 [online]. Available at: https://doi.org/10.3389/fimmu.2019.01827